Christianity wouldn't have its framework without these essential doctrines.
Inspiration of Scripture
Most Christians realize the inspiration of God’s word is an essential doctrine. J. Gresham Machen, pastor, professor and author of “Christianity and Liberalism,” expressed scripture as
a “true account” of divine revelation whose entire text is ensured by the Holy Spirit.
From the days of the Old Testament through today, the historic view of God’s people is that “God has spoken.” Not only has He spoken, but He has done so in a way that is without mistakes.
He did this through “inspiration,” most clearly stated by Paul in 2 Timothy 3:16:
All Scripture is inspired by God and is profitable for teaching, for rebuking, for correcting, for training in righteousness. (HSCB)
The doctrine of inspiration is what gives us assurance God has given us His Word, and that it absolutely trustworthy for every aspect of our lives. (Inspiration does not guarantee infallible interpretation, but that’s a topic for another day.)
God Is Holy
Scripture speaks of God’s holiness many times. At its core, holiness means to be set apart for a special purpose. When speaking of God, holiness is an attribute. That is, holiness isn’t something God does—it’s part of His being. He hasn’t been set apart; He sets apart. Without holiness He would cease to be the God revealed in scripture.
From holy ground to holy days to holy people to holy places to be in relationship with God was to be set apart for His glory: to be holy. God’s holiness was reflected in the various things set apart for His use. His people were instructed to be holy for the very reason that God Himself is holy. Even the word we translate church means “called-out ones.” ...
Read Source: 99 Essential Doctrines Christians Should Know